| D.E.肖D. E. Shaw & Co., Inc. |
| <0.01% | <0.01% | #21 | $674.2万 | 4,095.9万股 | $12.8万 | 38.9万股 | +4,057.0万股+10,417.73% | 加仓 |
| 683 Capital Management, LLC |
| 0.32% | 0.09% | #3 | $645.2万 | 3,919.9万股 | $164.3万 | 500.0万股 | +3,419.9万股+683.98% | 加仓 |
| DeepCurrents Investment 集团DeepCurrents Investment Group LLC |
| 0.21% | — | #4 | $602.6万 | 3,766.5万股 | $0 | 0股 | +3,766.5万股 | 新买入 |
| 语境资本管理Context Capital Management, LLC |
| 0.09% | — | #12 | $476.5万 | 2,894.6万股 | $0 | 0股 | +2,894.6万股 | 新买入 |
| Worth Venture Partners, LLC |
| 8.71% | — | #1 | $411.8万 | 2,501.8万股 | $0 | 0股 | +2,501.8万股 | 新买入 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #42 | $257.3万 | 1,563.0万股 | $332.7万 | 1,012.7万股 | +550.3万股+54.34% | 加仓 |
| GSA CAPITAL PARTNERS LLP |
| 0.16% | 0.07% | #6 | $246.7万 | 1,498.7万股 | $106.9万 | 325.4万股 | +1,173.3万股+360.54% | 加仓 |
| Wolverine资产管理WOLVERINE ASSET MANAGEMENT LLC |
| 0.02% | <0.01% | #13 | $212.2万 | 1,289.5万股 | $2,956 | 9,000股 | +1,288.6万股+143,174.96% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #23 | $191.4万 | 1,163.0万股 | $40.0万 | 121.8万股 | +1,041.2万股+854.94% | 加仓 |
| Kalehua Capital Management LLC |
| 1.32% | 2.38% | #2 | $183.5万 | 1,114.9万股 | $336.3万 | 1,023.6万股 | +91.3万股+8.92% | 加仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #104 | $155.4万 | 941.6万股 | $309.1万 | 939.5万股 | +2.1万股+0.23% | 加仓 |
| ARCH Venture Management, LLC |
| 0.12% | 0.39% | #7 | $132.6万 | 805.6万股 | $264.6万 | 805.6万股 | 00.00% | 持仓不变 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #66 | $128.9万 | 783.3万股 | $100.7万 | 306.6万股 | +476.7万股+155.48% | 加仓 |
| Octagon Capital Advisors LP |
| 0.11% | 0.28% | #8 | $127.6万 | 775.0万股 | $254.6万 | 775.0万股 | 00.00% | 持仓不变 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #122 | $126.2万 | 767.0万股 | $552.8万 | 1,682.7万股 | -915.7万股-54.42% | 减仓 |
| 箭街资本ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| <0.01% | — | #50 | $124.7万 | 757.3万股 | $0 | 0股 | +757.3万股 | 新买入 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #43 | $122.3万 | 743.2万股 | $157.1万 | 478.1万股 | +265.1万股+55.45% | 加仓 |
| Samsara BioCapital, LLC |
| 0.1% | 0.23% | #10 | $118.9万 | 722.3万股 | $237.3万 | 722.3万股 | 00.00% | 持仓不变 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #38 | $116.3万 | 706.6万股 | $161.5万 | 491.8万股 | +214.8万股+43.68% | 加仓 |
| Corient私人财富Corient Private Wealth LLC |
| <0.01% | <0.01% | #47 | $92.6万 | 562.6万股 | $130.9万 | 398.5万股 | +164.0万股+41.15% | 加仓 |
| Siren, L.L.C. |
| 0.02% | 0.05% | #14 | $85.7万 | 520.9万股 | $171.1万 | 520.9万股 | 00.00% | 持仓不变 |
| 高瓴资本Hillhouse Capital Advisors, Ltd. |
| 0.1% | 0.1% | #9 | $81.9万 | 497.4万股 | $163.4万 | 497.4万股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #89 | $51.0万 | 309.4万股 | $62.0万 | 188.4万股 | +121.0万股+64.25% | 加仓 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | <0.01% | #54 | $42.1万 | 255.6万股 | $111.6万 | 339.9万股 | -84.2万股-24.78% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #115 | $40.9万 | 248.2万股 | $162.3万 | 494.0万股 | -245.8万股-49.76% | 减仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #74 | $39.5万 | 240.3万股 | $6.2万 | 18.7万股 | +221.5万股+1,181.96% | 加仓 |
| MB Generational Wealth, LLC |
| 0.18% | 0.28% | #5 | $36.5万 | 221.7万股 | $50.3万 | 153.2万股 | +68.5万股+44.73% | 加仓 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| <0.01% | <0.01% | #35 | $36.0万 | 218.7万股 | $55.7万 | 169.5万股 | +49.2万股+29.04% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | — | #64 | $33.8万 | 211.5万股 | $0 | 0股 | +211.5万股 | 新买入 |
| Alyeska投资集团Alyeska Investment Group, L.P. |
| <0.01% | <0.01% | #44 | $33.8万 | 205.1万股 | $67.4万 | 205.1万股 | 00.00% | 持仓不变 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #60 | $29.5万 | 179.2万股 | $172.9万 | 527.8万股 | -348.6万股-66.04% | 减仓 |
| 汇丰控股HSBC HOLDINGS PLC |
| <0.01% | <0.01% | #77 | $26.7万 | 158.3万股 | $3.8万 | 11.4万股 | +146.9万股+1,289.39% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #121 | $25.6万 | 159.1万股 | $52.4万 | 158.9万股 | +1,976股+0.12% | 加仓 |
| Ensign Peak顾问Ensign Peak Advisors, Inc |
| <0.01% | <0.01% | #56 | $23.9万 | 145.1万股 | $55.9万 | 170.2万股 | -25.1万股-14.75% | 减仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #96 | $20.5万 | 124.5万股 | $46.2万 | 140.4万股 | -15.9万股-11.31% | 减仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #135 | $20.1万 | 122.9万股 | $3.0万 | 9.3万股 | +113.6万股+1,225.53% | 加仓 |
| DEUTSCHE 银行 AG\DEUTSCHE BANK AG\ |
| <0.01% | <0.01% | #93 | $18.8万 | 110.6万股 | $43.1万 | 130.6万股 | -19.9万股-15.27% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #126 | $18.6万 | 112.8万股 | $38.8万 | 118.1万股 | -5.2万股-4.41% | 减仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #147 | $18.3万 | 111.5万股 | $144.1万 | 438.8万股 | -327.3万股-74.60% | 减仓 |
| Hennion & Walsh Asset Management, Inc. |
| 0.01% | 0.01% | #18 | $18.1万 | 109.9万股 | $27.2万 | 82.9万股 | +27.0万股+32.60% | 加仓 |
| NEA Management Company, LLC |
| 0.01% | 0.02% | #15 | $16.5万 | 100.0万股 | $32.9万 | 100.0万股 | 00.00% | 持仓不变 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #116 | $16.3万 | 99.3万股 | $49.6万 | 151.0万股 | -51.8万股-34.27% | 减仓 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #84 | $15.3万 | 92.7万股 | $24.2万 | 73.5万股 | +19.2万股+26.07% | 加仓 |
| SMITH, MOORE & CO. |
| 0.01% | 0.01% | #16 | $14.8万 | 90.0万股 | $15.4万 | 47.0万股 | +43.0万股+91.49% | 加仓 |
| Ishara Investments LP |
| 0.1% | 0.26% | #11 | $13.5万 | 82.0万股 | $26.9万 | 82.0万股 | 00.00% | 持仓不变 |
| PanAgora资产管理PANAGORA ASSET MANAGEMENT INC |
| <0.01% | <0.01% | #57 | $12.1万 | 73.3万股 | $15.4万 | 47.0万股 | +26.3万股+56.02% | 加仓 |
| MarinerMariner, LLC |
| <0.01% | <0.01% | #80 | $9.8万 | 59.5万股 | $13.7万 | 41.8万股 | +17.6万股+42.14% | 加仓 |
| IEQ资本IEQ CAPITAL, LLC |
| <0.01% | <0.01% | #55 | $9.7万 | 59.1万股 | $12.9万 | 39.4万股 | +19.8万股+50.16% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #152 | $9.0万 | 54.4万股 | $71.1万 | 216.1万股 | -161.7万股-74.82% | 减仓 |
| Choreo资本CHOREO, LLC |
| <0.01% | <0.01% | #40 | $8.9万 | 54.0万股 | $8.2万 | 25.0万股 | +29.0万股+115.95% | 加仓 |
