| RA资本管理RA CAPITAL MANAGEMENT, L.P. |
| 0.49% | 0.52% | #2 | $5,605.0万 | 2,099.3万股 | $4,954.3万 | 2,099.3万股 | 00.00% | 持仓不变 |
| Sands Capital Alternatives, LLC |
| 1.62% | 2.08% | #1 | $993.3万 | 372.0万股 | $877.9万 | 372.0万股 | 00.00% | 持仓不变 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #49 | $664.9万 | 249.0万股 | $42.1万 | 17.8万股 | +231.2万股+1,296.38% | 加仓 |
| Alyeska投资集团Alyeska Investment Group, L.P. |
| 0.02% | 0.02% | #11 | $655.4万 | 245.5万股 | $577.7万 | 245.5万股 | 00.00% | 持仓不变 |
| 富兰克林资源FRANKLIN RESOURCES INC |
| <0.01% | <0.01% | #25 | $615.5万 | 230.5万股 | $544.0万 | 230.5万股 | 00.00% | 持仓不变 |
| ADAR1 Capital Management, LLC |
| 0.26% | 0.3% | #5 | $563.7万 | 211.1万股 | $508.9万 | 215.6万股 | -4.5万股-2.09% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #51 | $446.4万 | 167.2万股 | $355.5万 | 150.6万股 | +16.6万股+11.01% | 加仓 |
| Knollwood Investment Advisory, LLC |
| 0.39% | 0.39% | #3 | $434.8万 | 162.9万股 | $384.3万 | 162.9万股 | 00.00% | 持仓不变 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #41 | $304.9万 | 114.2万股 | $98.3万 | 41.6万股 | +72.6万股+174.33% | 加仓 |
| Ikarian Capital, LLC |
| 0.3% | 0.2% | #4 | $281.4万 | 105.4万股 | $248.7万 | 105.4万股 | 00.00% | 持仓不变 |
| 哈德逊湾资本管理Hudson Bay Capital Management LP |
| 0.01% | 0.01% | #16 | $255.0万 | 95.5万股 | $228.7万 | 96.9万股 | -1.4万股-1.44% | 减仓 |
| Pathstone控股Pathstone Holdings, LLC |
| 0.01% | 0.01% | #17 | $229.4万 | 85.9万股 | $202.8万 | 85.9万股 | 00.00% | 持仓不变 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #22 | $180.2万 | 67.5万股 | $111.9万 | 47.4万股 | +20.1万股+42.43% | 加仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #26 | $166.3万 | 62.3万股 | $125.3万 | 53.1万股 | +9.2万股+17.35% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #57 | $160.3万 | 60.1万股 | $35.8万 | 15.2万股 | +44.9万股+295.79% | 加仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #47 | $96.3万 | 36.1万股 | $17.8万 | 7.5万股 | +28.6万股+379.64% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | — | #64 | $85.7万 | 32.1万股 | $0 | 0股 | +32.1万股 | 新买入 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #43 | $77.9万 | 29.2万股 | $28.2万 | 12.0万股 | +17.2万股+143.46% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #40 | $77.8万 | 29.1万股 | $47.0万 | 19.9万股 | +9.2万股+46.19% | 加仓 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #58 | $73.4万 | 27.5万股 | $75.6万 | 32.0万股 | -4.5万股-14.19% | 减仓 |
| 布斯湾基金管理BOOTHBAY FUND MANAGEMENT, LLC |
| 0.01% | 0.01% | #12 | $72.9万 | 27.3万股 | $64.4万 | 27.3万股 | 00.00% | 持仓不变 |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #30 | $72.2万 | 27.0万股 | $43.5万 | 18.6万股 | +8.4万股+45.46% | 加仓 |
| 野村控股NOMURA HOLDINGS INC |
| <0.01% | — | #32 | $50.7万 | 19.0万股 | $0 | 0股 | +19.0万股 | 新买入 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #65 | $49.5万 | 18.6万股 | $168.4万 | 71.3万股 | -52.8万股-74.00% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #60 | $49.1万 | 18.4万股 | $48.8万 | 20.7万股 | -2.3万股-11.01% | 减仓 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| 0.01% | 0.01% | #14 | $47.0万 | 17.6万股 | $41.6万 | 17.6万股 | 00.00% | 持仓不变 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #75 | $36.5万 | 13.7万股 | $25.5万 | 14.9万股 | -1.3万股-8.46% | 减仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | — | #56 | $33.2万 | 12.4万股 | $0 | 0股 | +12.4万股 | 新买入 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | — | #61 | $30.7万 | 11.5万股 | $0 | 0股 | +11.5万股 | 新买入 |
| PFG 投资PFG Investments, LLC |
| 0.01% | 0.01% | #13 | $25.2万 | 9.4万股 | $19.1万 | 8.1万股 | +1.3万股+16.57% | 加仓 |
| CATALYST FINANCIAL PARTNERS LLC |
| 0.02% | 0.02% | #10 | $23.9万 | 9.0万股 | $21.2万 | 9.0万股 | 00.00% | 持仓不变 |
| 纽文Nuveen, LLC |
| <0.01% | — | #62 | $16.9万 | 6.3万股 | $0 | 0股 | +6.3万股 | 新买入 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #55 | $16.2万 | 6.1万股 | $155.7万 | 66.0万股 | -59.9万股-90.81% | 减仓 |
| SquarepointSquarepoint Ops LLC |
| <0.01% | <0.01% | #42 | $14.0万 | 5.2万股 | $3.5万 | 1.5万股 | +3.7万股+248.66% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #78 | $13.6万 | 5.1万股 | $2.8万 | 1.2万股 | +3.9万股+325.41% | 加仓 |
| 繁荣金融服务Prospera Financial Services Inc |
| <0.01% | <0.01% | #23 | $13.4万 | 5.0万股 | $11.8万 | 5.0万股 | 00.00% | 持仓不变 |
| 富国银行WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #73 | $13.3万 | 5.0万股 | $2.4万 | 1.0万股 | +4.0万股+391.55% | 加仓 |
| 马歇尔·韦斯MARSHALL WACE, LLP |
| <0.01% | <0.01% | #48 | $12.8万 | 4.8万股 | $45.5万 | 19.3万股 | -14.5万股-75.06% | 减仓 |
| DEUTSCHE 银行 AG\DEUTSCHE BANK AG\ |
| <0.01% | — | #67 | $12.3万 | 4.6万股 | $0 | 0股 | +4.6万股 | 新买入 |
| Verdad Advisers, LP |
| 0.11% | 0.1% | #6 | $11.9万 | 4.4万股 | $8.8万 | 3.7万股 | +7,200股+19.31% | 加仓 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #74 | $10.6万 | 4.0万股 | $7.2万 | 3.1万股 | +8,976股+29.26% | 加仓 |
| 普信集团PRICE T ROWE ASSOCIATES INC /MD/ |
| <0.01% | — | #82 | $10.5万 | 3.9万股 | $0 | 0股 | +3.9万股 | 新买入 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | <0.01% | #50 | $10.3万 | 3.9万股 | $28.4万 | 12.0万股 | -8.2万股-67.93% | 减仓 |
| 纽约州共同退休基金NEW YORK STATE COMMON RETIREMENT FUND |
| <0.01% | — | #46 | $9.7万 | 3.6万股 | $0 | 0股 | +3.6万股 | 新买入 |
| RhumbLine顾问RHUMBLINE ADVISERS |
| <0.01% | — | #53 | $9.4万 | 3.5万股 | $0 | 0股 | +3.5万股 | 新买入 |
| Rangeley Capital, LLC |
| 0.09% | 0.08% | #7 | $9.3万 | 3.5万股 | $8.3万 | 3.5万股 | 00.00% | 持仓不变 |
| XTX资本XTX Topco Ltd |
| <0.01% | — | #28 | $8.6万 | 3.2万股 | $0 | 0股 | +3.2万股 | 新买入 |
| Intrepid Financial Planning Group LLC |
| 0.03% | 0.03% | #9 | $8.1万 | 3.0万股 | $7.1万 | 3.0万股 | 00.00% | 持仓不变 |
| Y截距(香港)Y-Intercept (Hong Kong) Ltd |
| <0.01% | — | #24 | $7.9万 | 3.0万股 | $0 | 0股 | +3.0万股 | 新买入 |
| Quantinno资本管理Quantinno Capital Management LP |
| <0.01% | — | #52 | $7.1万 | 2.7万股 | $0 | 0股 | +2.7万股 | 新买入 |
