| Federated HermesFEDERATED HERMES, INC. |
| 0.1% | 0.06% | #17 | $6,755.1万 | 1,299.1万股 | $3,962.2万 | 1,299.1万股 | 00.00% | 持仓不变 |
| RA资本管理RA CAPITAL MANAGEMENT, L.P. |
| 0.43% | 0.3% | #8 | $4,911.4万 | 944.5万股 | $2,799.9万 | 918.0万股 | +26.5万股+2.89% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #73 | $4,013.5万 | 771.8万股 | $1,925.6万 | 631.4万股 | +140.5万股+22.25% | 加仓 |
| Opaleye Management Inc. |
| 2.97% | 2.53% | #2 | $3,276.0万 | 630.0万股 | $1,921.5万 | 630.0万股 | 00.00% | 持仓不变 |
| Balyasny资产管理BALYASNY ASSET MANAGEMENT L.P. |
| 0.03% | 0.02% | #22 | $2,424.3万 | 466.2万股 | $1,539.8万 | 504.8万股 | -38.6万股-7.65% | 减仓 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #78 | $1,994.6万 | 383.6万股 | $1,074.2万 | 352.2万股 | +31.4万股+8.91% | 加仓 |
| Siren, L.L.C. |
| 0.35% | 0.28% | #9 | $1,730.7万 | 332.8万股 | $1,015.1万 | 332.8万股 | 00.00% | 持仓不变 |
| Jacobs Levy股票管理JACOBS LEVY EQUITY MANAGEMENT, INC |
| 0.05% | <0.01% | #20 | $1,332.1万 | 256.2万股 | $67.2万 | 22.0万股 | +234.1万股+1,062.24% | 加仓 |
| 詹尼森联营JENNISON ASSOCIATES LLC |
| 0.01% | 0.01% | #33 | $1,278.8万 | 245.9万股 | $1,048.9万 | 343.9万股 | -98.0万股-28.49% | 减仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #71 | $1,128.8万 | 217.0万股 | $599.3万 | 196.4万股 | +20.6万股+10.48% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #91 | $962.1万 | 185.0万股 | $540.4万 | 177.2万股 | +7.8万股+4.42% | 加仓 |
| D.E.肖D. E. Shaw & Co., Inc. |
| <0.01% | <0.01% | #38 | $956.5万 | 183.9万股 | $538.6万 | 176.6万股 | +7.3万股+4.16% | 加仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #75 | $841.8万 | 161.9万股 | $317.6万 | 33.8万股 | +128.1万股+379.04% | 加仓 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #70 | $826.1万 | 158.9万股 | $331.7万 | 108.7万股 | +50.1万股+46.09% | 加仓 |
| 先锋领航组合管理VANGUARD PORTFOLIO MANAGEMENT LLC |
| <0.01% | <0.01% | #87 | $718.0万 | 138.1万股 | $909.4万 | 298.2万股 | -160.1万股-53.69% | 减仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | <0.01% | #72 | $684.7万 | 131.7万股 | $183.7万 | 60.2万股 | +71.4万股+118.63% | 加仓 |
| Squadron Capital Management LLC |
| 2.1% | — | #4 | $677.8万 | 130.3万股 | $0 | 0股 | +130.3万股 | 新买入 |
| 纽文Nuveen, LLC |
| <0.01% | <0.01% | #49 | $673.5万 | 129.5万股 | $29.8万 | 9.8万股 | +119.8万股+1,225.89% | 加仓 |
| 肯尼迪资本管理KENNEDY CAPITAL MANAGEMENT LLC |
| 0.11% | 0.08% | #13 | $635.3万 | 122.2万股 | $377.0万 | 123.6万股 | -1.4万股-1.17% | 减仓 |
| 黑石集团Blackstone Inc. |
| 0.02% | — | #27 | $563.1万 | 108.3万股 | $0 | 0股 | +108.3万股 | 新买入 |
| AQR资本管理AQR CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #44 | $524.1万 | 100.8万股 | $243.0万 | 79.7万股 | +21.1万股+26.52% | 加仓 |
| Affinity Asset Advisors, LLC |
| 0.24% | 0.24% | #11 | $520.0万 | 100.0万股 | $472.0万 | 154.8万股 | -54.8万股-35.39% | 减仓 |
| GREAT POINT PARTNERS LLC |
| 0.94% | 0.67% | #6 | $494.9万 | 95.2万股 | $290.3万 | 95.2万股 | 00.00% | 持仓不变 |
| Ikarian Capital, LLC |
| 0.52% | <0.01% | #7 | $486.2万 | 93.5万股 | $5.0万 | 1.6万股 | +91.9万股+5,573.96% | 加仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #63 | $463.2万 | 89.1万股 | $161.7万 | 53.0万股 | +36.1万股+67.99% | 加仓 |
| 22NW, LP |
| 4.08% | 1.97% | #1 | $426.7万 | 82.1万股 | $250.3万 | 82.1万股 | 00.00% | 持仓不变 |
| Velan Capital Investment Management LP |
| 2.38% | 1.43% | #3 | $390.0万 | 75.0万股 | $228.8万 | 75.0万股 | 00.00% | 持仓不变 |
| 美国银行BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #94 | $379.8万 | 73.0万股 | $906.0万 | 297.1万股 | -224.0万股-75.41% | 减仓 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #76 | $377.1万 | 72.5万股 | $193.0万 | 63.3万股 | +9.2万股+14.61% | 加仓 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #74 | $376.3万 | 72.4万股 | $194.7万 | 63.8万股 | +8.5万股+13.35% | 加仓 |
| Woodline合伙人Woodline Partners LP |
| 0.01% | 0.01% | #30 | $318.1万 | 61.2万股 | $186.6万 | 61.2万股 | 00.00% | 持仓不变 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #68 | $296.9万 | 57.1万股 | $182.9万 | 60.0万股 | -2.9万股-4.80% | 减仓 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #59 | $269.0万 | 51.7万股 | $462.9万 | 151.8万股 | -100.0万股-65.92% | 减仓 |
| J. Goldman & Co LP |
| 0.07% | 0.05% | #18 | $260.2万 | 50.0万股 | $178.7万 | 58.6万股 | -8.5万股-14.59% | 减仓 |
| Integral Health 资产管理Integral Health Asset Management, LLC |
| 0.1% | 0.29% | #14 | $260.0万 | 50.0万股 | $610.0万 | 200.0万股 | -150.0万股-75.00% | 减仓 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #86 | $257.9万 | 49.6万股 | $591.1万 | 193.8万股 | -144.2万股-74.41% | 减仓 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #47 | $224.2万 | 43.1万股 | $253.3万 | 83.1万股 | -40.0万股-48.10% | 减仓 |
| Vestal Point 资本Vestal Point Capital, LP |
| 0.05% | — | #21 | $199.2万 | 38.3万股 | $0 | 0股 | +38.3万股 | 新买入 |
| Knott David M Jr |
| 1.03% | 0.68% | #5 | $192.4万 | 37.0万股 | $112.9万 | 37.0万股 | 00.00% | 持仓不变 |
| XTX资本XTX Topco Ltd |
| 0.02% | 0.02% | #24 | $183.9万 | 35.4万股 | $89.3万 | 29.3万股 | +6.1万股+20.78% | 加仓 |
| 木星资产管理Jupiter Topco LLC |
| <0.01% | — | #66 | $172.8万 | 33.2万股 | $0 | 0股 | +33.2万股 | 新买入 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #98 | $167.7万 | 32.3万股 | $60.4万 | 19.8万股 | +12.4万股+62.84% | 加仓 |
| Driehaus资本管理DRIEHAUS CAPITAL MANAGEMENT LLC |
| 0.01% | — | #32 | $150.5万 | 29.0万股 | $0 | 0股 | +29.0万股 | 新买入 |
| 布斯湾基金管理BOOTHBAY FUND MANAGEMENT, LLC |
| 0.02% | — | #26 | $149.2万 | 28.7万股 | $0 | 0股 | +28.7万股 | 新买入 |
| 萨斯奎汉纳组合策略Susquehanna Portfolio Strategies, LLC |
| 0.02% | 0.01% | #25 | $145.4万 | 28.0万股 | $34.9万 | 11.4万股 | +16.5万股+144.59% | 加仓 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #109 | $137.2万 | 26.4万股 | $172.4万 | 56.5万股 | -30.1万股-53.33% | 减仓 |
| Schonfeld战略顾问Schonfeld Strategic Advisors LLC |
| <0.01% | — | #36 | $137.1万 | 26.4万股 | $0 | 0股 | +26.4万股 | 新买入 |
| 富达投资FMR LLC |
| <0.01% | <0.01% | #128 | $112.4万 | 21.6万股 | $17.5万 | 5.7万股 | +15.9万股+276.73% | 加仓 |
| 纽约梅隆银行Bank of New York Mellon Corp |
| <0.01% | <0.01% | #100 | $110.4万 | 21.2万股 | $57.9万 | 19.0万股 | +2.2万股+11.85% | 加仓 |
| 罗素投资集团Russell Investments Group, Ltd. |
| <0.01% | <0.01% | #62 | $109.2万 | 21.0万股 | $14.1万 | 4.6万股 | +16.4万股+355.52% | 加仓 |
