| GSK plc |
| 3.37% | 3.59% | #1 | $2,031.1万 | 919.1万股 | $2,150.6万 | 919.1万股 | 00.00% | 持仓不变 |
| PFIZER INC |
| 3.13% | 2.31% | #2 | $533.9万 | 236.2万股 | $550.4万 | 236.2万股 | 00.00% | 持仓不变 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #29 | $450.0万 | 203.6万股 | $421.2万 | 180.0万股 | +23.6万股+13.13% | 加仓 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #12 | $209.5万 | 94.8万股 | $278.3万 | 118.9万股 | -24.1万股-20.29% | 减仓 |
| Alphabet公司Alphabet Inc. |
| 0.05% | 0.05% | #4 | $208.3万 | 89.0万股 | $208.3万 | 89.0万股 | 00.00% | 持仓不变 |
| 萨斯奎汉纳国际集团SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #27 | $178.5万 | 80.8万股 | $89.3万 | 38.2万股 | +42.6万股+111.62% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #44 | $131.4万 | 59.4万股 | $101.4万 | 43.3万股 | +16.1万股+37.21% | 加仓 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #32 | $125.2万 | 56.6万股 | $121.7万 | 52.0万股 | +4.6万股+8.93% | 加仓 |
| 雷蒙德詹姆斯金融RAYMOND JAMES FINANCIAL INC |
| <0.01% | — | #24 | $115.3万 | 52.2万股 | $0 | 0股 | +52.2万股 | 新买入 |
| Two Sigma投资TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #21 | $84.6万 | 38.3万股 | $207.2万 | 88.6万股 | -50.3万股-56.77% | 减仓 |
| 箭街资本ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
| <0.01% | — | #23 | $73.6万 | 33.3万股 | $0 | 0股 | +33.3万股 | 新买入 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #26 | $63.6万 | 28.8万股 | $61.8万 | 26.4万股 | +2.4万股+8.91% | 加仓 |
| GSA CAPITAL PARTNERS LLP |
| 0.04% | 0.04% | #5 | $63.2万 | 28.6万股 | $65.1万 | 27.8万股 | +7,602股+2.73% | 加仓 |
| 维度基金顾问DIMENSIONAL FUND ADVISORS LP |
| <0.01% | <0.01% | #28 | $60.8万 | 27.5万股 | $6.9万 | 3.0万股 | +24.5万股+823.21% | 加仓 |
| 高盛集团GOLDMAN SACHS GROUP INC |
| <0.01% | — | #35 | $56.8万 | 25.7万股 | $0 | 0股 | +25.7万股 | 新买入 |
| 简街集团JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #36 | $51.3万 | 23.2万股 | $42.7万 | 18.3万股 | +4.9万股+27.02% | 加仓 |
| 道富集团STATE STREET CORP |
| <0.01% | <0.01% | #47 | $47.5万 | 21.5万股 | $50.3万 | 21.5万股 | 00.00% | 持仓不变 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #37 | $30.9万 | 14.0万股 | $7,041 | 3,009股 | +13.7万股+4,542.07% | 加仓 |
| 桥道资本管理BRIDGEWAY CAPITAL MANAGEMENT, LLC |
| <0.01% | 0.01% | #11 | $25.4万 | 11.5万股 | $26.9万 | 11.5万股 | 00.00% | 持仓不变 |
| 北方信托NORTHERN TRUST CORP |
| <0.01% | <0.01% | #41 | $23.9万 | 10.8万股 | $28.3万 | 12.1万股 | -1.3万股-10.51% | 减仓 |
| Point72资产管理Point72 Asset Management, L.P. |
| <0.01% | <0.01% | #25 | $23.1万 | 10.4万股 | $14.0万 | 6.0万股 | +4.5万股+74.93% | 加仓 |
| Ionic Capital Management LLC |
| 0.03% | 0.03% | #6 | $22.7万 | 10.3万股 | $45.8万 | 19.6万股 | -9.3万股-47.59% | 减仓 |
| 魁北克Desjardins联合会Federation des caisses Desjardins du Quebec |
| <0.01% | — | #20 | $20.2万 | 9.2万股 | $0 | 0股 | +9.2万股 | 新买入 |
| Shay Capital LLC |
| 0.01% | 0.01% | #8 | $16.0万 | 7.2万股 | $16.5万 | 7.0万股 | +2,037股+2.90% | 加仓 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #45 | $14.5万 | 6.6万股 | $99.6万 | 42.6万股 | -36.0万股-84.59% | 减仓 |
| 景顺Invesco Ltd. |
| <0.01% | <0.01% | #49 | $14.2万 | 6.4万股 | $10.6万 | 4.5万股 | +1.9万股+41.59% | 加仓 |
| Simplex交易SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #30 | $13.5万 | 6.1万股 | $7.1万 | 3.0万股 | +3.1万股+102.32% | 加仓 |
| Verdad Advisers, LP |
| 0.11% | 0.09% | #3 | $11.3万 | 5.1万股 | $7.8万 | 3.3万股 | +1.8万股+53.44% | 加仓 |
| XTX资本XTX Topco Ltd |
| <0.01% | — | #15 | $11.2万 | 5.1万股 | $0 | 0股 | +5.1万股 | 新买入 |
| 美国世纪投资AMERICAN CENTURY COMPANIES INC |
| <0.01% | — | #38 | $8.1万 | 3.7万股 | $0 | 0股 | +3.7万股 | 新买入 |
| Capital Asset 咨询服务Capital Asset Advisory Services LLC |
| <0.01% | <0.01% | #13 | $7.2万 | 3.3万股 | $9.2万 | 3.3万股 | 00.00% | 持仓不变 |
| Axxcess财富管理AXXCESS WEALTH MANAGEMENT, LLC |
| <0.01% | — | #16 | $7.2万 | 3.3万股 | $0 | 0股 | +3.3万股 | 新买入 |
| Three Seasons Wealth, LLC |
| 0.01% | 0.03% | #10 | $6.6万 | 3.0万股 | $7.0万 | 3.0万股 | 00.00% | 持仓不变 |
| 嘉信理财CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
| <0.01% | <0.01% | #50 | $6.3万 | 2.9万股 | $6.7万 | 2.9万股 | 00.00% | 持仓不变 |
| 先锋环球顾问Vanguard Global Advisers, LLC |
| <0.01% | <0.01% | #42 | $5.6万 | 2.5万股 | $6.0万 | 2.5万股 | 00.00% | 持仓不变 |
| 全球退休合伙人Global Retirement Partners, LLC |
| <0.01% | — | #17 | $5.5万 | 2.5万股 | $0 | 0股 | +2.5万股 | 新买入 |
| 奥本海默公司OPPENHEIMER & CO INC |
| <0.01% | — | #22 | $5.0万 | 2.3万股 | $0 | 0股 | +2.3万股 | 新买入 |
| 千禧管理MILLENNIUM MANAGEMENT LLC |
| <0.01% | — | #46 | $4.3万 | 1.9万股 | $0 | 0股 | +1.9万股 | 新买入 |
| Assenagon资产管理Assenagon Asset Management S.A. |
| <0.01% | <0.01% | #34 | $4.1万 | 1.9万股 | $4.4万 | 1.9万股 | 00.00% | 持仓不变 |
| DLK Investment Management, LLC |
| 0.02% | — | #7 | $4.1万 | 3.1万股 | $0 | 0股 | +3.1万股 | 新买入 |
| 萨斯奎汉纳组合策略Susquehanna Portfolio Strategies, LLC |
| <0.01% | — | #19 | $3.9万 | 1.8万股 | $0 | 0股 | +1.8万股 | 新买入 |
| 萨斯奎汉纳基本面投资SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC |
| <0.01% | — | #18 | $3.6万 | 1.6万股 | $0 | 0股 | +1.6万股 | 新买入 |
| Qube研究科技Qube Research & Technologies Ltd |
| <0.01% | — | #40 | $3.0万 | 1.4万股 | $0 | 0股 | +1.4万股 | 新买入 |
| SG Americas Securities, LLC |
| <0.01% | — | #48 | $2.5万 | 1.1万股 | $0 | 0股 | +1.1万股 | 新买入 |
| Group One交易GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #39 | $2.4万 | 1.1万股 | $4.3万 | 1.8万股 | -7,531股-40.93% | 减仓 |
| TWO SIGMA SECURITIES, LLC |
| <0.01% | — | #14 | $2.3万 | 1.1万股 | $0 | 0股 | +1.1万股 | 新买入 |
| 保德信金融PRUDENTIAL FINANCIAL INC |
| <0.01% | — | #43 | $2.3万 | 1.0万股 | $0 | 0股 | +1.0万股 | 新买入 |
| 花旗集团CITIGROUP INC |
| <0.01% | <0.01% | #51 | $2.1万 | 9,625股 | $4.5万 | 1.9万股 | -9,510股-49.70% | 减仓 |
| FNY Investment Advisers, LLC |
| 0.01% | 0.01% | #9 | $1.8万 | 8,300股 | $1.2万 | 5,300股 | +3,000股+56.60% | 加仓 |
| 琼斯金融JONES FINANCIAL COMPANIES LLLP |
| <0.01% | <0.01% | #52 | $1.7万 | 7,678股 | $1.8万 | 7,678股 | 00.00% | 持仓不变 |
