| Sofinnova Investments, Inc. |
| 0.03% | 0.02% | #4 | $53.0万 | 13.8万股 | $55.6万 | 13.8万股 | 00.00% | 持仓不变 |
| 文艺复兴科技RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #10 | $38.0万 | 9.9万股 | $31.2万 | 7.7万股 | +2.1万股+27.71% | 加仓 |
| Vivo Capital, LLC |
| 0.03% | 0.02% | #6 | $27.9万 | 7.2万股 | $29.3万 | 7.2万股 | 00.00% | 持仓不变 |
| 城堡顾问CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #13 | $21.9万 | 5.7万股 | $4.1万 | 1.0万股 | +4.7万股+462.89% | 加仓 |
| T3 Companies, LLC |
| 0.16% | 0.17% | #1 | $14.6万 | 3.8万股 | $15.4万 | 3.8万股 | 00.00% | 持仓不变 |
| Board of Trustees of The Leland Stanford Junior University |
| 0.03% | 0.02% | #5 | $13.9万 | 3.6万股 | $14.5万 | 3.6万股 | 00.00% | 持仓不变 |
| PFIZER INC |
| 0.08% | 0.06% | #3 | $13.4万 | 3.1万股 | $13.7万 | 3.1万股 | 00.00% | 持仓不变 |
| Lynx1 Capital Management LP |
| 0.02% | 0.02% | #7 | $11.9万 | 3.1万股 | $12.4万 | 3.1万股 | 00.00% | 持仓不变 |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P |
| 0.08% | 0.1% | #2 | $10.6万 | 2.8万股 | $11.1万 | 2.8万股 | 00.00% | 持仓不变 |
| Geode资本管理GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #15 | $7.4万 | 1.9万股 | $11.6万 | 2.9万股 | -9,672股-33.59% | 减仓 |
| Shay Capital LLC |
| <0.01% | 0.01% | #9 | $5.9万 | 1.5万股 | $6.0万 | 1.5万股 | +533股+3.58% | 加仓 |
| 贝莱德BlackRock, Inc. |
| <0.01% | <0.01% | #20 | $3.7万 | 9,711股 | $3.9万 | 9,711股 | 00.00% | 持仓不变 |
| 先锋领航VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #19 | $2.7万 | 7,060股 | $2.9万 | 7,060股 | 00.00% | 持仓不变 |
| Nan Fung Group Holdings Ltd |
| 0.01% | 0.1% | #8 | $1.9万 | 5,000股 | $11.8万 | 2.9万股 | -2.4万股-82.91% | 减仓 |
| 摩根士丹利MORGAN STANLEY |
| <0.01% | <0.01% | #18 | $1.2万 | 3,145股 | $1.7万 | 3,128股 | +17股+0.54% | 加仓 |
| 先锋信托VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #16 | $1.2万 | 3,095股 | $1.3万 | 3,095股 | 00.00% | 持仓不变 |
| NewEdge顾问NewEdge Advisors, LLC |
| <0.01% | — | #12 | $9,740 | 2,530股 | $0 | 0股 | +2,530股 | 新买入 |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #11 | $6,584 | 1,710股 | $4,416 | 1,093股 | +617股+56.45% | 加仓 |
| 美世全球顾问MERCER GLOBAL ADVISORS INC /ADV |
| <0.01% | — | #17 | $1,124 | 292股 | $0 | 0股 | +292股 | 新买入 |
| 瑞银集团UBS Group AG |
| <0.01% | <0.01% | #21 | $982 | 255股 | $3,179 | 787股 | -532股-67.60% | 减仓 |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #14 | $501 | 130股 | $40 | 10股 | +120股+1,200.00% | 加仓 |
| 摩根大通JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #23 | $165 | 42股 | $179 | 42股 | 00.00% | 持仓不变 |
| 花旗集团CITIGROUP INC |
| <0.01% | — | #22 | $158 | 41股 | $0 | 0股 | +41股 | 新买入 |
| 巴克莱BARCLAYS PLC |
| <0.01% | <0.01% | #24 | $23 | 6股 | $24 | 6股 | 00.00% | 持仓不变 |
