| Pavaki Capital Management LLC |
| 4.24% | — | #3 | $12.2M | 9.1M | $0 | 0 | +9.1M | New Buy |
| RTW INVESTMENTS, LP |
| 0.09% | 0.07% | #6 | $10.5M | 7.8M | $7.5M | 6.3M | +1.5M+23.73% | Add |
| Propel Bio Management, LLC |
| 5.21% | 3.2% | #2 | $10.0M | 7.4M | $5.1M | 4.1M | +3.3M+80.40% | Add |
| Point72 Asset Management, L.P. |
| 0.01% | <0.01% | #18 | $7.3M | 5.4M | $1.3M | 1.1M | +4.3M+398.41% | Add |
| Simplify Asset Management Inc. |
| 0.06% | 0.03% | #8 | $4.5M | 3.3M | $1.8M | 1.5M | +1.8M+122.34% | Add |
| MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #33 | $4.2M | 3.1M | $1.8M | 1.5M | +1.6M+103.47% | Add |
| TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #29 | $2.7M | 2.0M | $2.8M | 2.3M | -277,161-11.96% | Reduce |
| MARSHALL WACE, LLP |
| <0.01% | <0.01% | #31 | $2.4M | 1.8M | $2.3M | 1.9M | -146,835-7.55% | Reduce |
| Kalehua Capital Management LLC |
| 1.22% | — | #4 | $1.7M | 1.3M | $0 | 0 | +1.3M | New Buy |
| Lion Point Capital, LP |
| 5.26% | 5.83% | #1 | $1.1M | 820,000 | $975,800 | 820,000 | 00.00% | Unchanged |
| TORONTO DOMINION BANK |
| <0.01% | <0.01% | #35 | $1.0M | 750,000 | $892,500 | 750,000 | 00.00% | Unchanged |
| AMERIPRISE FINANCIAL INC |
| <0.01% | — | #45 | $893,332 | 666,666 | $0 | 0 | +666,666 | New Buy |
| Boxer Capital Management, LLC |
| 0.07% | 0.1% | #7 | $893,332 | 666,666 | $793,333 | 666,666 | 00.00% | Unchanged |
| MORGAN STANLEY |
| <0.01% | <0.01% | #55 | $851,183 | 635,211 | $5.9M | 3.0M | -2.3M-78.61% | Reduce |
| UBS Group AG |
| <0.01% | <0.01% | #51 | $623,641 | 465,403 | $588,940 | 494,908 | -29,505-5.96% | Reduce |
| BOOTHBAY FUND MANAGEMENT, LLC |
| 0.01% | <0.01% | #17 | $619,976 | 462,669 | $200,723 | 168,675 | +293,994+174.30% | Add |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #58 | $529,025 | 394,795 | $748,684 | 629,146 | -234,351-37.25% | Reduce |
| Aptus Capital Advisors, LLC |
| <0.01% | <0.01% | #26 | $455,533 | 339,950 | $333,498 | 280,250 | +59,700+21.30% | Add |
| GUARDIAN WEALTH ADVISORS, LLC / NC |
| 0.03% | 0.02% | #12 | $454,863 | 339,450 | $333,498 | 280,250 | +59,200+21.12% | Add |
| Seven Fleet Capital Management LP |
| 0.06% | 0.13% | #9 | $362,112 | 270,233 | $396,666 | 333,333 | -63,100-18.93% | Reduce |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #59 | $339,405 | 253,287 | $412,568 | 346,696 | -93,409-26.94% | Reduce |
| Squarepoint Ops LLC |
| <0.01% | <0.01% | #44 | $310,644 | 231,824 | $400,822 | 336,825 | -105,001-31.17% | Reduce |
| LPL Financial LLC |
| <0.01% | <0.01% | #52 | $295,970 | 220,873 | $230,114 | 193,373 | +27,500+14.22% | Add |
| BALYASNY ASSET MANAGEMENT L.P. |
| <0.01% | <0.01% | #43 | $295,467 | 220,498 | $1.0M | 851,325 | -630,827-74.10% | Reduce |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #48 | $232,763 | 173,704 | $210,040 | 176,504 | -2,800-1.59% | Reduce |
| TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC |
| 0.11% | 0.07% | #5 | $201,000 | 150,000 | $119,000 | 100,000 | +50,000+50.00% | Add |
| Wealthspire Advisors, LLC |
| <0.01% | <0.01% | #36 | $188,443 | 140,629 | $12,649 | 10,629 | +130,000+1,223.07% | Add |
| Valeo Financial Advisors, LLC |
| <0.01% | <0.01% | #25 | $175,137 | 130,699 | $155,532 | 130,699 | 00.00% | Unchanged |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #68 | $140,683 | 104,987 | $239,391 | 201,169 | -96,182-47.81% | Reduce |
| ADAR1 Capital Management, LLC |
| 0.01% | 0.01% | #20 | $134,000 | 100,000 | $119,000 | 100,000 | 00.00% | Unchanged |
| Cascades Capital Asset Management, LLC |
| 0.04% | — | #11 | $112,037 | 83,610 | $0 | 0 | +83,610 | New Buy |
| Quadrature Capital Ltd |
| <0.01% | <0.01% | #38 | $86,646 | 64,661 | $177,435 | 149,105 | -84,444-56.63% | Reduce |
| SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #56 | $72,589 | 54,171 | $177,656 | 149,291 | -95,120-63.71% | Reduce |
| Bay Rivers Group |
| 0.02% | 0.01% | #13 | $62,488 | 46,633 | $35,594 | 29,911 | +16,722+55.91% | Add |
| SG Americas Securities, LLC |
| <0.01% | <0.01% | #61 | $61,069 | 45,574 | $51,000 | 42,512 | +3,062+7.20% | Add |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #74 | $54,657 | 40,789 | $48,538 | 40,789 | 00.00% | Unchanged |
| October Effect Ltd |
| 0.05% | 0.07% | #10 | $53,600 | 40,000 | $61,821 | 51,950 | -11,950-23.00% | Reduce |
| Focus Partners Wealth |
| <0.01% | <0.01% | #54 | $48,240 | 36,000 | $42,840 | 36,000 | 00.00% | Unchanged |
| RAYMOND JAMES FINANCIAL INC |
| <0.01% | <0.01% | #69 | $40,294 | 30,070 | $31,654 | 26,600 | +3,470+13.05% | Add |
| Federation des caisses Desjardins du Quebec |
| <0.01% | <0.01% | #47 | $39,907 | 29,781 | $35,439 | 29,781 | 00.00% | Unchanged |
| Mariner, LLC |
| <0.01% | <0.01% | #60 | $37,192 | 27,830 | $36,688 | 30,830 | -3,000-9.73% | Reduce |
| XTX Topco Ltd |
| <0.01% | <0.01% | #41 | $35,265 | 26,317 | $143,516 | 120,602 | -94,285-78.18% | Reduce |
| WELCH & FORBES LLC |
| <0.01% | <0.01% | #42 | $33,500 | 25,000 | $29,750 | 25,000 | 00.00% | Unchanged |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #37 | $32,408 | 24,185 | $10,885 | 9,147 | +15,038+164.40% | Add |
| NATIONAL BANK OF CANADA /FI/ |
| <0.01% | <0.01% | #62 | $31,490 | 23,500 | $27,965 | 23,500 | 00.00% | Unchanged |
| IMC-Chicago, LLC |
| <0.01% | <0.01% | #72 | $31,088 | 23,200 | $13,022 | 10,943 | +12,257+112.01% | Add |
| Exit Wealth Advisors, LLC. |
| 0.01% | 0.01% | #15 | $30,407 | 22,692 | $17,850 | 15,000 | +7,692+51.28% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #77 | $30,236 | 22,564 | $26,574 | 22,331 | +233+1.04% | Add |
| HighTower Advisors, LLC |
| <0.01% | <0.01% | #64 | $26,800 | 20,000 | $11,900 | 10,000 | +10,000+100.00% | Add |
| Stephenson & Company, Inc. |
| 0.01% | 0.01% | #16 | $26,800 | 20,000 | $23,800 | 20,000 | 00.00% | Unchanged |
