| ADAR1 Capital Management, LLC |
| 0.09% | 0.04% | #4 | $1.9M | 3.0M | $635,680 | 1.1M | +1.9M+177.28% | Add |
| Nantahala Capital Management, LLC |
| 0.04% | 0.04% | #7 | $1.3M | 2.0M | $1.2M | 2.0M | 00.00% | Unchanged |
| Lynx1 Capital Management LP |
| 0.21% | 0.15% | #3 | $1.1M | 1.6M | $973,148 | 1.6M | 00.00% | Unchanged |
| Shay Capital LLC |
| 0.06% | 0.08% | #6 | $947,843 | 1.5M | $962,120 | 1.6M | -153,591-9.54% | Reduce |
| T3 Companies, LLC |
| 0.66% | 0.62% | #1 | $614,912 | 945,000 | $564,638 | 945,000 | 00.00% | Unchanged |
| BRAIDWELL LP |
| 0.02% | 0.02% | #9 | $596,091 | 916,077 | $547,356 | 916,077 | 00.00% | Unchanged |
| KVP Capital Advisors, LP |
| 0.24% | 0.22% | #2 | $325,709 | 500,551 | $299,079 | 500,551 | 00.00% | Unchanged |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #24 | $304,825 | 468,457 | $307,380 | 514,443 | -45,986-8.94% | Reduce |
| TWO SIGMA INVESTMENTS, LP |
| <0.01% | <0.01% | #22 | $285,539 | 438,818 | $254,781 | 426,412 | +12,406+2.91% | Add |
| ACADIAN ASSET MANAGEMENT LLC |
| <0.01% | <0.01% | #18 | $248,435 | 381,797 | $228,000 | 381,797 | 00.00% | Unchanged |
| Ikarian Capital, LLC |
| 0.02% | 0.01% | #10 | $172,379 | 264,912 | $158,284 | 264,912 | 00.00% | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #31 | $172,227 | 264,557 | $158,205 | 264,557 | 00.00% | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #28 | $168,017 | 258,203 | $192,824 | 322,711 | -64,508-19.99% | Reduce |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #25 | $119,421 | 183,443 | $109,699 | 183,443 | 00.00% | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #29 | $77,405 | 118,957 | $34,526 | 57,784 | +61,173+105.86% | Add |
| Rangeley Capital, LLC |
| 0.07% | 0.07% | #5 | $73,571 | 113,064 | $70,543 | 118,064 | -5,000-4.23% | Reduce |
| XTX Topco Ltd |
| <0.01% | <0.01% | #16 | $51,224 | 78,721 | $94,642 | 158,396 | -79,675-50.30% | Reduce |
| GSA CAPITAL PARTNERS LLP |
| <0.01% | — | #12 | $46,547 | 71,533 | $0 | 0 | +71,533 | New Buy |
| SUPERSTRING CAPITAL MANAGEMENT LP |
| 0.03% | — | #8 | $39,868 | 61,269 | $0 | 0 | +61,269 | New Buy |
| UBS Group AG |
| <0.01% | <0.01% | #30 | $38,147 | 58,597 | $107,511 | 179,784 | -121,187-67.41% | Reduce |
| STALEY CAPITAL ADVISERS INC |
| <0.01% | <0.01% | #14 | $33,493 | 51,472 | $30,755 | 51,472 | 00.00% | Unchanged |
| BlackRock, Inc. |
| <0.01% | <0.01% | #36 | $28,895 | 44,405 | $26,532 | 44,405 | 00.00% | Unchanged |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #32 | $28,421 | 43,677 | $13,808 | 23,110 | +20,567+89.00% | Add |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #34 | $26,662 | 40,974 | $57,148 | 95,645 | -54,671-57.16% | Reduce |
| TWO SIGMA SECURITIES, LLC |
| <0.01% | — | #13 | $26,482 | 40,697 | $0 | 0 | +40,697 | New Buy |
| FNY Investment Advisers, LLC |
| 0.01% | 0.01% | #11 | $22,775 | 35,000 | $20,000 | 35,000 | 00.00% | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #26 | $15,161 | 23,300 | $10,337 | 17,300 | +6,000+34.68% | Add |
| COMMONWEALTH EQUITY SERVICES, LLC |
| <0.01% | <0.01% | #27 | $11,910 | 18,298 | $10,930 | 18,298 | 00.00% | Unchanged |
| STATE STREET CORP |
| <0.01% | <0.01% | #37 | $10,258 | 15,765 | $9,420 | 15,765 | 00.00% | Unchanged |
| Anson Funds Management LP |
| <0.01% | 0.06% | #17 | $9,406 | 14,455 | $742,756 | 1.2M | -1.2M-98.84% | Reduce |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #21 | $8,455 | 12,994 | $2,107 | 3,527 | +9,467+268.42% | Add |
| Harvest Investment Services, LLC |
| <0.01% | <0.01% | #15 | $7,196 | 11,059 | $6,608 | 11,059 | 00.00% | Unchanged |
| ACORN CAPITAL ADVISORS, LLC |
| <0.01% | <0.01% | #19 | $926 | 1,425 | $855 | 1,425 | 00.00% | Unchanged |
| MB, LEVIS & ASSOCIATES, LLC |
| <0.01% | <0.01% | #20 | $677 | 1,041 | $622 | 1,041 | 00.00% | Unchanged |
| Hurley Capital, LLC |
| <0.01% | <0.01% | #23 | $365 | 561 | $335 | 561 | 00.00% | Unchanged |
| BARCLAYS PLC |
| <0.01% | — | #40 | $92 | 141 | $0 | 0 | +141 | New Buy |
| WELLS FARGO & COMPANY/MN |
| <0.01% | <0.01% | #41 | $42 | 65 | $39 | 65 | 00.00% | Unchanged |
| MORGAN STANLEY |
| <0.01% | <0.01% | #43 | $28 | 43 | $305 | 911 | -868-95.28% | Reduce |
| Truvestments Capital LLC |
| <0.01% | <0.01% | #33 | $16 | 25 | $15 | 25 | 00.00% | Unchanged |
| NFSG Corp |
| <0.01% | <0.01% | #35 | $7 | 10 | $6 | 10 | 00.00% | Unchanged |
| JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #44 | $5 | 8 | $86 | 146 | -138-94.52% | Reduce |
| Steward Partners Investment Advisory, LLC |
| <0.01% | — | #42 | $1 | 1 | $0 | 0 | +1 | New Buy |
| Larson Financial Group LLC |
| <0.01% | <0.01% | #39 | $1 | 2 | $1 | 2 | 00.00% | Unchanged |
| FLAGSHIP WEALTH ADVISORS, LLC |
| <0.01% | — | #38 | $1 | 1 | $0 | 0 | +1 | New Buy |
