| Velan Capital Investment Management LP |
| 0.68% | 1.46% | #2 | $1.1M | 2.7M | $2.3M | 2.7M | 00.00% | Unchanged |
| ACORN CAPITAL ADVISORS, LLC |
| 0.16% | 0.35% | #3 | $604,027 | 1.4M | $1.2M | 1.4M | +26,667+1.89% | Add |
| KINGDON CAPITAL MANAGEMENT, L.L.C. |
| 0.06% | 0.13% | #4 | $569,237 | 1.4M | $1.2M | 1.4M | 00.00% | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC |
| <0.01% | <0.01% | #27 | $493,421 | 1.2M | $1.0M | 1.2M | -576-0.05% | Reduce |
| Rock Springs Capital Management LP |
| 0.02% | 0.06% | #5 | $463,406 | 1.1M | $964,456 | 1.1M | 00.00% | Unchanged |
| Carlyle Group Inc. |
| <0.01% | 0.01% | #9 | $448,866 | 1.1M | $934,195 | 1.1M | 00.00% | Unchanged |
| GSA CAPITAL PARTNERS LLP |
| 0.01% | <0.01% | #6 | $225,107 | 534,697 | $17,000 | 19,084 | +515,613+2,701.81% | Add |
| MILLENNIUM MANAGEMENT LLC |
| <0.01% | <0.01% | #20 | $204,999 | 486,933 | $1.4M | 1.6M | -1.1M-69.90% | Reduce |
| Lion Point Capital, LP |
| 0.94% | 2.44% | #1 | $195,765 | 465,000 | $407,433 | 465,000 | 00.00% | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC |
| <0.01% | <0.01% | #30 | $111,086 | 263,808 | $278,394 | 317,677 | -53,869-16.96% | Reduce |
| RENAISSANCE TECHNOLOGIES LLC |
| <0.01% | <0.01% | #16 | $100,156 | 237,900 | $155,526 | 177,500 | +60,400+34.03% | Add |
| CITADEL ADVISORS LLC |
| <0.01% | <0.01% | #26 | $96,156 | 228,400 | $64,927 | 74,100 | +154,300+208.23% | Add |
| JANE STREET GROUP, LLC |
| <0.01% | <0.01% | #29 | $78,030 | 185,343 | $88,071 | 100,515 | +84,828+84.39% | Add |
| BlackRock, Inc. |
| <0.01% | <0.01% | #36 | $71,413 | 169,627 | $212,093 | 242,061 | -72,434-29.92% | Reduce |
| VANGUARD FIDUCIARY TRUST CO |
| <0.01% | <0.01% | #23 | $63,126 | 149,943 | $131,350 | 149,943 | 00.00% | Unchanged |
| ADAR1 Capital Management, LLC |
| <0.01% | 0.01% | #10 | $58,940 | 140,000 | $122,668 | 140,000 | 00.00% | Unchanged |
| Quarry LP |
| <0.01% | 0.02% | #8 | $55,374 | 131,529 | $115,246 | 131,529 | 00.00% | Unchanged |
| UBS Group AG |
| <0.01% | <0.01% | #31 | $24,737 | 58,759 | $71,058 | 81,117 | -22,358-27.56% | Reduce |
| READYSTATE ASSET MANAGEMENT LP |
| <0.01% | <0.01% | #12 | $24,095 | 27,499 | $24,095 | 27,499 | 00.00% | Unchanged |
| Jain Global LLC |
| <0.01% | <0.01% | #18 | $21,549 | 51,185 | $15,791 | 18,022 | +33,163+184.01% | Add |
| OSAIC HOLDINGS, INC. |
| <0.01% | <0.01% | #22 | $19,298 | 45,850 | $35,793 | 40,850 | +5,000+12.24% | Add |
| STATE STREET CORP |
| <0.01% | <0.01% | #38 | $18,818 | 44,699 | $39,165 | 44,699 | 00.00% | Unchanged |
| NORTHERN TRUST CORP |
| <0.01% | <0.01% | #33 | $17,632 | 41,882 | $30,295 | 34,576 | +7,306+21.13% | Add |
| DIKER MANAGEMENT LLC |
| 0.01% | 0.03% | #7 | $15,000 | 35,000 | $30,667 | 35,000 | 00.00% | Unchanged |
| Qube Research & Technologies Ltd |
| <0.01% | — | #24 | $14,197 | 33,722 | $0 | 0 | +33,722 | New Buy |
| XTX Topco Ltd |
| <0.01% | <0.01% | #15 | $14,064 | 33,406 | $34,549 | 39,431 | -6,025-15.28% | Reduce |
| Rehmann Capital Advisory Group |
| <0.01% | <0.01% | #14 | $13,405 | 15,300 | $13,405 | 15,300 | 00.00% | Unchanged |
| SIMPLEX TRADING, LLC |
| <0.01% | <0.01% | #28 | $12,036 | 28,591 | $25,643 | 29,273 | -682-2.33% | Reduce |
| Ikarian Capital, LLC |
| <0.01% | <0.01% | #13 | $10,144 | 24,093 | $21,110 | 24,093 | 00.00% | Unchanged |
| GROUP ONE TRADING LLC |
| <0.01% | <0.01% | #25 | $8,391 | 19,930 | $775 | 885 | +19,045+2,151.98% | Add |
| Sequent Planning LLC |
| <0.01% | <0.01% | #11 | $6,273 | 14,900 | $13,055 | 14,900 | 00.00% | Unchanged |
| BANK OF AMERICA CORP /DE/ |
| <0.01% | <0.01% | #39 | $5,975 | 14,192 | $256,895 | 293,259 | -279,067-95.16% | Reduce |
| IEQ CAPITAL, LLC |
| <0.01% | <0.01% | #21 | $5,699 | 13,538 | $45,061 | 51,428 | -37,890-73.68% | Reduce |
| Engineers Gate Manager LP |
| <0.01% | <0.01% | #19 | $5,468 | 12,989 | $22,896 | 26,131 | -13,142-50.29% | Reduce |
| LPL Financial LLC |
| <0.01% | <0.01% | #35 | $5,157 | 12,250 | $10,733 | 12,250 | 00.00% | Unchanged |
| SG Americas Securities, LLC |
| <0.01% | — | #32 | $4,444 | 10,556 | $0 | 0 | +10,556 | New Buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
| <0.01% | <0.01% | #40 | $4,326 | 10,300 | $9,769 | 11,149 | -849-7.62% | Reduce |
| Tower Research Capital LLC (TRC) |
| <0.01% | <0.01% | #17 | $3,930 | 9,336 | $5,524 | 6,305 | +3,031+48.07% | Add |
| MORGAN STANLEY |
| <0.01% | <0.01% | #43 | $726 | 1,724 | $1,880 | 789,960 | -788,236-99.78% | Reduce |
| Arax Advisory Partners |
| <0.01% | — | #34 | $241 | 573 | $0 | 0 | +573 | New Buy |
| FEDERATED HERMES, INC. |
| <0.01% | <0.01% | #41 | $80 | 189 | $3,389 | 3,868 | -3,679-95.11% | Reduce |
| NATIONAL BANK OF CANADA /FI/ |
| <0.01% | <0.01% | #42 | $63 | 160 | $139 | 160 | 00.00% | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS |
| <0.01% | <0.01% | #44 | $59 | 141 | $124 | 141 | 00.00% | Unchanged |
| SBI Securities Co., Ltd. |
| <0.01% | <0.01% | #37 | $27 | 64 | $57 | 65 | -1-1.54% | Reduce |
| JONES FINANCIAL COMPANIES LLLP |
| <0.01% | <0.01% | #45 | $17 | 50 | $53 | 50 | 00.00% | Unchanged |
| JPMORGAN CHASE & CO |
| <0.01% | <0.01% | #46 | $4 | 9 | $8 | 9 | 00.00% | Unchanged |
