| MMIRUM PHARMACEUTICALS INCMIRM |
| 19.58% | 18.25% | $899.1M | 7.7M | $709.4M | 7.7M | 00.00% | Unchanged |
| NNEWAMSTERDAM PHARMA COMPANYNAMS |
| 13.35% | 13.96% | $613.0M | 18.1M | $542.4M | 16.9M | +1.1M+6.76% | Add |
| EERASCA INCERAS |
| 9.96% | 10.27% | $457.5M | 25.0M | $399.2M | 24.7M | +300,000+1.22% | Add |
| MMBX BIOSCIENCES INCMBX |
| 8% | 5.11% | $367.2M | 6.7M | $198.6M | 6.7M | 00.00% | Unchanged |
 ARCUTIS BIOTHERAPEUTICS INCARQT |
| 5.64% | 5.99% | $258.9M | 9.9M | $232.6M | 9.9M | 00.00% | Unchanged |
 TREVI THERAPEUTICS INCTRVI |
| 4.04% | 3.05% | $185.4M | 9.9M | $118.6M | 9.9M | -100-0.00% | Reduce |
 KRYSTAL BIOTECH INCKRYS |
| 3.9% | 3.2% | $178.9M | 481,307 | $124.3M | 481,307 | 00.00% | Unchanged |
| MMAZE THERAPEUTICS INCMAZE |
| 3.27% | 3.51% | $150.2M | 5.0M | $136.3M | 4.6M | +465,641+10.20% | Add |
| PPHATHOM PHARMACEUTICALS INCPHAT |
| 2.95% | 3.56% | $135.3M | 12.5M | $138.5M | 12.5M | 00.00% | Unchanged |
 PALVELLA THERAPEUTICS INC NEPVLA |
| 2.94% | 2.83% | $134.8M | 882,400 | $110.0M | 882,400 | 00.00% | Unchanged |
 BRIDGEBIO PHARMA INCBBIO |
| 2.51% | 6.59% | $115.3M | 1.5M | $256.1M | 3.4M | -1.9M-55.10% | Reduce |
 DISC MEDICINE INCIRON |
| 2.16% | 2.23% | $99.1M | 1.4M | $86.6M | 1.4M | 00.00% | Unchanged |
 CYTOKINETICS INCCYTK |
| 2.15% | 1.97% | $98.8M | 1.2M | $76.4M | 1.2M | 00.00% | Unchanged |
| DDYNE THERAPEUTICS INCDYN |
| 1.53% | 1.47% | $70.0M | 3.2M | $57.2M | 3.2M | 00.00% | Unchanged |
| AASCENDIS PHARMA A/S SPONSORED ADRASND |
| 1.31% | 0.78% | $60.1M | 225,155 | $30.5M | 133,333 | +91,822+68.87% | Add |
| SSAVARA INCSVRA |
| 1.3% | 1.37% | $59.9M | 9.7M | $53.1M | 9.7M | 00.00% | Unchanged |
| PPARABILIS MEDICINES INCPBLS |
| 1.14% | — | $52.6M | 1.9M | $0 | 0 | +1.9M | New Buy |
| AAURA BIOSCIENCES INCAURA |
| 1.1% | 0.88% | $50.4M | 7.1M | $34.1M | 5.1M | +2.0M+39.22% | Add |
| AACHIEVE LIFE SCIENCE INCACHV |
| 1.08% | — | $49.7M | 7.6M | $0 | 0 | +7.6M | New Buy |
| VVOR BIOPHARMA INCVOR |
| 1.02% | 1.17% | $46.8M | 2.5M | $45.4M | 2.5M | 00.00% | Unchanged |
| AALLOGENE THERAPEUTICS INC COMALLO |
| 1.02% | 0.24% | $46.7M | 22.4M | $9.3M | 3.8M | +18.7M+491.22% | Add |
| TTARSUS PHARMACEUTICALS INCTARS |
| 1% | 1.32% | $45.9M | 728,644 | $51.1M | 728,644 | 00.00% | Unchanged |
 BIOCRYST PHARMACEUTICALS INCBCRX |
| 0.87% | 0.98% | $40.1M | 4.0M | $38.2M | 4.0M | 00.00% | Unchanged |
 ALKERMES PLCALKS |
| 0.8% | 0.64% | $36.7M | 700,647 | $24.8M | 700,647 | 00.00% | Unchanged |
| AACADIA PHARMACEUTICALS INC COMACAD |
| 0.79% | 0.82% | $36.4M | 1.4M | $32.0M | 1.4M | 00.00% | Unchanged |
| ZZAI LAB LIMITED ADS EACH REP 10 ORD SHSZLAB |
| 0.79% | 0.92% | $36.1M | 1.9M | $35.8M | 1.9M | 00.00% | Unchanged |
 MANNKIND CORPMNKD |
| 0.61% | 0.37% | $28.1M | 6.6M | $14.5M | 5.9M | +700,000+11.86% | Add |
 DESIGN THERAPEUTICS INC COMDSGN |
| 0.57% | — | $26.2M | 1.8M | $0 | 0 | +1.8M | New Buy |
| AACLARIS THERAPEUTICS INC COMACRS |
| 0.57% | 0.48% | $26.1M | 4.9M | $18.5M | 4.9M | 00.00% | Unchanged |
| SSHATTUCK LABS INCSTTK |
| 0.57% | — | $26.0M | 3.8M | $0 | 0 | +3.8M | New Buy |
| KKAILERA THERAPEUTICS INCKLRA |
| 0.53% | — | $24.2M | 1.1M | $0 | 0 | +1.1M | New Buy |
| MMONTE ROSA THERAPEUTICS INCGLUE |
| 0.53% | 0.42% | $24.2M | 1.0M | $16.5M | 1.0M | 00.00% | Unchanged |
 LEXEO THERAPEUTICS INCLXEO |
| 0.49% | 0.65% | $22.5M | 4.8M | $25.4M | 4.4M | +400,000+9.04% | Add |
 RELAY THERAPEUTICS INCRLAY |
| 0.41% | — | $19.0M | 1.0M | $0 | 0 | +1.0M | New Buy |
| EEVOLUS INC COMEOLS |
| 0.4% | 0.28% | $18.3M | 2.6M | $10.8M | 2.6M | 00.00% | Unchanged |
| IIMMUNOCORE HLDGS PLCIMCR |
| 0.34% | 0.38% | $15.4M | 484,782 | $14.6M | 484,782 | 00.00% | Unchanged |
| VVALNEVA SE FUNSPONSORED ADR 1 ADR REPS 2 ORD SHSVALN |
| 0.26% | 0.37% | $12.0M | 2.3M | $14.3M | 2.3M | 00.00% | Unchanged |
| NNEWAMSTERDAM PHARMA COMPANY |
| 0.23% | 0.26% | $10.7M | 500,333 | $10.0M | 500,333 | 00.00% | Unchanged |
| AAUTOLUS THERAPEUTICS PLCAUTL |
| 0.15% | 0.16% | $7.1M | 4.4M | $6.1M | 4.4M | 00.00% | Unchanged |
| XXILIO THERAPEUTICS INCXLO |
| 0.09% | 0.09% | $4.0M | 422,505 | $3.6M | 422,505 | 00.00% | Unchanged |
| IIBIO INC CON NEWIBIO |
| 0.07% | 0.1% | $3.4M | 2.0M | $3.7M | 2.0M | 00.00% | Unchanged |
