BIOMARIN PHARMACEUTICAL INC BMRN
8.06% 5.65% $344.8M 6.0M $202.0M 3.6M +2.5M +68.53% Add NEUROCRINE BIOSCIENCES INC NBIX
7.4% 4.6% $316.8M 1.9M $164.7M 1.3M +630,000 +50.40% Add ABIVAX SA ABVX
7.32% 4.67% $313.1M 2.3M $167.0M 1.5M +849,443 +56.63% Add UNITED THERAPEUTICS CORP DEL UTHR
5.51% 1.24% $235.7M 435,000 $44.5M 75,000 +360,000 +480.00% Add E ENLIVEN THERAPEUTICS INC ELVN
4.74% 3.56% $203.0M 4.0M $127.4M 3.3M +750,000 +23.08% Add NURIX THERAPEUTICS INC NRIX
4.56% 2.82% $195.3M 8.1M $100.8M 6.5M +1.6M +23.85% Add B BICARA THERAPEUTICS INC BCAX
3.64% 3.02% $155.9M 5.3M $107.9M 5.4M -175,000 -3.23% Reduce TAYSHA GENE THERAPIES INC TSHA
3.09% 2.25% $132.2M 19.4M $80.5M 18.0M +1.4M +7.86% Add ARROWHEAD PHARMACEUTICALS IN ARWR
3% 3.99% $128.4M 1.6M $142.6M 2.3M -700,000 -30.77% Reduce ABBOTT LABORATORIES ABT
2.97% — $127.0M 1.4M $0 0 +1.4M New Buy ZIMMER BIOMET HOLDINGS INC ZBH
2.82% 0.48% $120.5M 1.4M $17.2M 190,000 +1.2M +636.84% Add DISC MEDICINE INC IRON
2.65% 1.25% $113.4M 1.6M $44.8M 700,000 +850,000 +121.43% Add M MONTE ROSA THERAPEUTICS INC GLUE
2.6% 1.66% $111.3M 4.6M $59.3M 3.6M +996,535 +27.65% Add INSULET CORP PODD
2.38% 0.3% $102.0M 670,000 $10.6M 50,601 +619,399 +1,224.08% Add A ASCENDIS PHARMA A/S SPONSORED ADR ASND
2.34% 2.4% $100.0M 375,000 $85.8M 375,000 0 0.00% Unchanged ASTRAZENECA PLC AZN
1.99% 0.55% $85.3M 450,000 $19.7M 100,000 +350,000 +350.00% Add S SANOFI SA SPONSORED ADR SNY
1.99% 1.89% $85.3M 2.0M $67.5M 1.4M +600,000 +42.86% Add R REVOLUTION MEDICINES INC COM RVMD
1.97% 6.46% $84.3M 450,000 $231.0M 2.4M -1.9M -81.05% Reduce BIOCRYST PHARMACEUTICALS INC BCRX
1.94% 1.87% $83.0M 8.3M $66.9M 7.0M +1.3M +18.15% Add D DYNE THERAPEUTICS INC DYN
1.75% 2.03% $75.0M 3.4M $72.5M 4.0M -625,000 -15.63% Reduce NEKTAR THERAPEUTICS COM NEW NKTR
1.63% 0.57% $69.8M 1.0M $20.5M 285,000 +715,000 +250.88% Add GLOBUS MED INC GMED
1.57% 1.47% $67.2M 850,000 $52.6M 610,520 +239,480 +39.23% Add T TARSUS PHARMACEUTICALS INC TARS
1.54% 0.39% $66.1M 1.1M $14.0M 200,000 +850,000 +425.00% Add IMMATICS N.V IMTX
1.46% 1.7% $62.6M 6.2M $60.8M 6.2M 0 0.00% Unchanged TREVI THERAPEUTICS INC TRVI
1.35% 0.72% $57.8M 3.1M $25.8M 2.2M +933,496 +43.09% Add I IMMUNOCORE HLDGS PLC IMCR
1.34% 2.33% $57.2M 1.8M $83.4M 2.8M -966,868 -34.94% Reduce R REPLIGEN CORP RGEN
1.28% 3.05% $54.6M 400,000 $109.0M 925,000 -525,000 -56.76% Reduce BRISTOL-MYERS SQUIBB CO BMY
1.08% 1.7% $46.1M 800,000 $60.7M 1.0M -200,000 -20.00% Reduce UNIQURE NV QURE
1.01% 0.16% $43.1M 935,000 $5.9M 358,996 +576,004 +160.45% Add XENON PHARMACEUTICALS INC XENE
0.99% 1.04% $42.3M 700,000 $37.2M 639,900 +60,100 +9.39% Add B BRIGHT MINDS BIOSCIENCES INC DRUG
0.89% 1% $38.3M 545,000 $35.9M 492,319 +52,681 +10.70% Add MADRIGAL PHARMACEUTICALS INC MDGL
0.82% 0.46% $34.9M 65,000 $16.5M 31,468 +33,532 +106.56% Add ALCON AG ORD SHS ALC
0.78% 1.69% $33.6M 500,000 $60.3M 800,000 -300,000 -37.50% Reduce M MYRIAD GENETICS INC COM MYGN
0.77% 0.21% $32.7M 5.7M $7.4M 1.6M +4.1M +248.00% Add R RAPPORT THERAPEUTICS INC RAPP
0.71% 1.26% $30.4M 730,000 $44.9M 1.4M -706,229 -49.17% Reduce C Crescent Biopharma Inc CBIO
0.69% 0.77% $29.3M 1.6M $27.6M 1.5M +130,000 +8.67% Add G GE HEALTHCARE TECHNOLOGIES I GEHC
0.67% 0.5% $28.8M 450,000 $17.8M 250,000 +200,000 +80.00% Add INSMED INC INSM
0.62% — $26.7M 250,000 $0 0 +250,000 New Buy V VIKING THERAPEUTICS INC VKTX
0.62% 0.83% $26.5M 680,000 $29.7M 914,147 -234,147 -25.61% Reduce B BETA BIONICS INC BBNX
0.59% 0.62% $25.1M 1.6M $22.2M 2.2M -611,518 -27.65% Reduce REGENERON PHARMACEUTICALS REGN
0.58% 0.86% $24.9M 40,000 $30.9M 40,000 0 0.00% Unchanged SOLID BIOSCIENCES INC SLDB
0.5% 1.01% $21.6M 2.2M $36.0M 5.0M -2.8M -56.80% Reduce A ALTO NEUROSCIENCE INC COM SHS ANRO
0.48% 1.3% $20.7M 785,000 $46.4M 2.1M -1.3M -61.97% Reduce F FIRST TRACKS BIOTHERAPEUTICS TRAX
0.48% — $20.4M 1.0M $0 0 +1.0M New Buy LEXEO THERAPEUTICS INC LXEO
0.47% 0.72% $20.1M 4.3M $25.7M 4.5M -155,000 -3.46% Reduce S SAVARA INC SVRA
0.39% 0.4% $16.8M 2.7M $14.2M 2.6M +119,948 +4.61% Add D DAMORA THERAPEUTICS INC DMRA
0.35% 0.43% $15.0M 575,000 $15.5M 600,000 -25,000 -4.17% Reduce S SPYGLASS PHARMA INC SGP
0.35% 0.48% $14.9M 670,000 $17.3M 666,760 +3,240 +0.49% Add TECTONIC THERAPEUTIC INC COM TECX
0.34% 0.28% $14.6M 425,000 $10.1M 328,000 +97,000 +29.57% Add AVALO THERAPEUTICS AVTX
0.33% — $14.3M 775,000 $0 0 +775,000 New Buy 
