C CELLDEX THERAPEUTICS INC NEW CLDX
10.95% 11.43% $198.1M 5.3M $185.3M 5.8M -517,659 -8.86% Reduce SYNDAX PHARMACEUTICALS INC SNDX
9.73% 11.6% $176.0M 8.1M $188.1M 8.1M 0 0.00% Unchanged VAXCYTE INC PCVX
9.39% 10.48% $169.9M 2.9M $169.8M 2.9M 0 0.00% Unchanged COGENT BIOSCIENCES INC COGT
7.84% 9.59% $141.9M 3.7M $155.4M 4.0M -370,234 -9.17% Reduce V VERA THERAPEUTICS INC VERA
6.85% 8.43% $124.0M 2.9M $136.7M 3.4M -508,165 -14.95% Reduce V VIRIDIAN THERAPEUTICS INC VRDN
6.55% 2.83% $118.6M 6.5M $45.8M 2.3M +4.1M +175.61% Add T TRAVERE THERAPEUTICS INC TVTX
6.28% 4.44% $113.6M 2.0M $72.0M 2.4M -423,918 -17.49% Reduce B BEAM THERAPEUTICS INC BEAM
5.39% 5.41% $97.5M 2.8M $87.7M 3.7M -841,393 -22.85% Reduce U UROGEN PHARMA LTD URGN
4.95% 2.49% $89.6M 2.4M $40.4M 2.2M +186,814 +8.31% Add L LEGEND BIOTECH CORP LEGN
4.79% 1.76% $86.7M 3.0M $28.5M 1.6M +1.4M +90.40% Add CYTOMX THERAPEUTICS INC. CTMX
4.5% 4.35% $81.4M 21.7M $70.6M 15.0M +6.7M +44.56% Add RELAY THERAPEUTICS INC RLAY
3.41% 0.87% $61.7M 3.3M $14.2M 1.4M +1.9M +131.70% Add C CULLINAN THERAPEUTICS INC CGEM
3.13% 2.73% $56.7M 3.1M $44.3M 3.1M 0 0.00% Unchanged M MBX BIOSCIENCES INC MBX
2.85% 1.72% $51.6M 934,799 $27.9M 934,799 0 0.00% Unchanged I IMMUNOCORE HLDGS PLC IMCR
2.41% 1.65% $43.7M 1.4M $26.7M 884,937 +490,063 +55.38% Add NURIX THERAPEUTICS INC NRIX
1.6% 1.14% $29.0M 1.2M $18.5M 1.2M 0 0.00% Unchanged S SUTRO BIOPHARMA INC STRO
1.6% 1.34% $29.0M 872,558 $21.7M 872,558 0 0.00% Unchanged BIOCRYST PHARMACEUTICALS INC BCRX
1.39% 3.34% $25.2M 2.5M $54.1M 5.7M -3.2M -55.59% Reduce PHARVARIS N V PHVS
1.26% 1.12% $22.9M 661,795 $18.1M 640,395 +21,400 +3.34% Add S SUMMIT THERAPEUTICS INC COM SMMT
0.97% — $17.5M 1.2M $0 0 +1.2M New Buy P PRELUDE THERAPEUTICS INC COM PRLD
0.71% 0.34% $12.9M 2.4M $5.4M 1.6M +822,536 +51.65% Add INSMED INC INSM
0.59% — $10.7M 100,000 $0 0 +100,000 New Buy B BURNING ROCK BIOTECH LTD BNR
0.58% 1.22% $10.5M 1.2M $19.8M 1.2M +11,008 +0.90% Add G GERON CORP GERN
0.48% 0.63% $8.8M 6.8M $10.2M 6.8M 0 0.00% Unchanged A AMARIN CORP PLC AMRN
0.47% 0.42% $8.5M 532,982 $6.8M 472,382 +60,600 +12.83% Add A ALECTOR INC COM ALEC
0.42% 0.27% $7.7M 3.8M $4.3M 2.0M +1.8M +90.42% Add P PARABILIS MEDICINES INC PBLS
0.38% — $6.8M 250,000 $0 0 +250,000 New Buy C CARIBOU BIOSCIENCES INC COM CRBU
0.24% 0.29% $4.4M 2.5M $4.8M 2.5M 0 0.00% Unchanged P PROQR THRAPEUTICS N V
0.16% 0.16% $2.9M 1.6M $2.5M 1.6M 0 0.00% Unchanged C CANDEL THERAPEUTICS INC COM CADL
0.06% 0.06% $996,432 96,741 $980,000 200,000 -103,259 -51.63% Reduce E ENGENE THERAPEUTICS INC ENGN
0.04% — $792,089 457,855 $0 0 +457,855 New Buy T TRAWS PHARMA INC TRAW
<0.01% — $71,175 84,400 $0 0 +84,400 New Buy 
