| EERASCA INCERAS |
| 9.58% | 9.01% | $222.6M | 12.2M | $180.4M | 11.2M | +1.0M+8.97% | Add |
 ABIVAX SAABVX |
| 5.87% | 3.75% | $136.5M | 1.0M | $75.2M | 675,000 | +349,000+51.70% | Add |
| RREVOLUTION MEDICINES INC COMRVMD |
| 5.64% | 9.71% | $131.1M | 700,000 | $194.5M | 2.0M | -1.3M-65.00% | Reduce |
 IDEAYA BIOSCIENCES INCIDYA |
| 4.81% | 5.74% | $111.8M | 3.0M | $115.0M | 3.5M | -450,000-13.04% | Reduce |
 BIONTECH SE FUNSPONSORED ADR 1 ADR REPS 1 ORD SHSBNTX |
| 4.07% | — | $94.4M | 1.0M | $0 | 0 | +1.0M | New Buy |
| VVERA THERAPEUTICS INCVERA |
| 4.06% | — | $94.4M | 2.2M | $0 | 0 | +2.2M | New Buy |
| TTANGO THERAPEUTICS INCTNGX |
| 3.84% | 3.13% | $89.1M | 2.9M | $62.8M | 3.0M | -150,000-5.00% | Reduce |
 PRAXIS PRECISION MEDICINES IPRAX |
| 3.75% | 4.58% | $87.0M | 260,000 | $91.8M | 285,000 | -25,000-8.77% | Reduce |
| CCELLDEX THERAPEUTICS INC NEWCLDX |
| 3.36% | 0.71% | $78.1M | 2.1M | $14.3M | 450,000 | +1.7M+366.67% | Add |
| DDIANTHUS THERAPEUTICS INCDNTH |
| 3.36% | 1.68% | $78.0M | 800,000 | $33.6M | 400,000 | +400,000+100.00% | Add |
 CG ONCOLOGY INCCGON |
| 3.06% | 1.94% | $71.1M | 1.0M | $38.9M | 575,000 | +425,000+73.91% | Add |
 DISC MEDICINE INCIRON |
| 2.76% | 1.79% | $64.0M | 875,000 | $35.8M | 560,000 | +315,000+56.25% | Add |
| MMAZE THERAPEUTICS INCMAZE |
| 2.49% | 1.84% | $57.7M | 1.9M | $36.9M | 1.2M | +700,000+56.68% | Add |
| DDYNE THERAPEUTICS INCDYN |
| 2.44% | 1.27% | $56.6M | 2.6M | $25.4M | 1.4M | +1.2M+82.14% | Add |
| MMOONLAKE IMMUNOTHERAPEUTICSMLTX |
| 2.24% | 1.4% | $52.1M | 2.7M | $28.0M | 1.5M | +1.2M+78.33% | Add |
| OOCULAR THERAPEUTIX INCOCUL |
| 2.24% | 1.63% | $52.0M | 5.3M | $32.6M | 3.9M | +1.5M+37.66% | Add |
 DESIGN THERAPEUTICS INC COMDSGN |
| 1.87% | 1.04% | $43.4M | 3.0M | $20.7M | 2.0M | +1.1M+53.85% | Add |
| OOLEMA PHARMACEUTICALS INC COMOLMA |
| 1.73% | 2.39% | $40.1M | 3.2M | $47.8M | 3.2M | 00.00% | Unchanged |
 BELITE BIO INCBLTE |
| 1.66% | — | $38.5M | 250,000 | $0 | 0 | +250,000 | New Buy |
| AACHIEVE LIFE SCIENCE INCACHV |
| 1.53% | — | $35.4M | 5.4M | $0 | 0 | +5.4M | New Buy |
 TREVI THERAPEUTICS INCTRVI |
| 1.51% | 1.43% | $35.1M | 1.9M | $28.6M | 2.4M | -520,000-21.67% | Reduce |
 COGENT BIOSCIENCES INCCOGT |
| 1.5% | — | $34.8M | 900,000 | $0 | 0 | +900,000 | New Buy |
| AARRIVENT BIOPHARMA INCAVBP |
| 1.5% | 0.4% | $34.7M | 1.0M | $8.1M | 350,000 | +650,000+185.71% | Add |
| CCrescent Biopharma IncCBIO |
| 1.47% | 0.44% | $34.2M | 1.9M | $8.9M | 482,500 | +1.4M+293.78% | Add |
 COMPASS PATHWAYS ADR A FUNSPONSORED ADR 1 ADR REPS 1 ORD SHSCMPS |
| 1.37% | — | $31.8M | 2.3M | $0 | 0 | +2.3M | New Buy |
 MINERALYS THERAPEUTICS INCMLYS |
| 1.22% | — | $28.3M | 1.1M | $0 | 0 | +1.1M | New Buy |
| RREPLIMUNE GROUP INCREPL |
| 1.19% | — | $27.7M | 2.5M | $0 | 0 | +2.5M | New Buy |
 XENON PHARMACEUTICALS INCXENE |
| 1.17% | 1.31% | $27.2M | 450,000 | $26.2M | 450,000 | 00.00% | Unchanged |
 STRUCTURE THERAPEUTICS INCGPCR |
| 1.16% | 1.2% | $26.8M | 500,000 | $24.1M | 500,000 | 00.00% | Unchanged |
| IIMMUNOVANT INCIMVT |
| 1.1% | 1.33% | $25.6M | 665,000 | $26.7M | 1.1M | -410,000-38.14% | Reduce |
 JADE BIOSCIENCES INCJBIO |
| 1.08% | 0.28% | $25.0M | 1.1M | $5.6M | 400,000 | +725,000+181.25% | Add |
| EENLIVEN THERAPEUTICS INCELVN |
| 1.02% | 2.04% | $23.6M | 465,000 | $40.8M | 1.0M | -575,000-55.29% | Reduce |
| VVERADERMICS INCMANE |
| 0.95% | 0.08% | $22.1M | 180,000 | $1.6M | 25,000 | +155,000+620.00% | Add |
 AVALO THERAPEUTICSAVTX |
| 0.91% | 0.97% | $21.3M | 1.2M | $19.4M | 1.3M | -150,000-11.54% | Reduce |
 ARCUS BIOSCIENCES INCRCUS |
| 0.86% | 1.29% | $20.0M | 650,000 | $25.9M | 1.2M | -550,000-45.83% | Reduce |
| SSUMMIT THERAPEUTICS INC COMSMMT |
| 0.85% | — | $19.7M | 1.4M | $0 | 0 | +1.4M | New Buy |
| IIMMUNOCORE HLDGS PLCIMCR |
| 0.82% | 2.26% | $19.1M | 600,000 | $45.2M | 1.5M | -900,000-60.00% | Reduce |
| LLB PHARMACEUTICALS INCLBRX |
| 0.82% | 1.13% | $19.0M | 585,000 | $22.6M | 915,000 | -330,000-36.07% | Reduce |
| MMINERVA NEUROSCIENCES INCNERV |
| 0.79% | 0.97% | $18.3M | 3.3M | $19.4M | 3.2M | +73,777+2.29% | Add |
| FFAETH THERAPEUTICS INCFTH |
| 0.78% | 0.05% | $18.1M | 722,020 | $945,600 | 30,000 | +692,020+2,306.73% | Add |
 CRISPR THERAPEUTICSCRSP |
| 0.7% | — | $16.4M | 300,000 | $0 | 0 | +300,000 | New Buy |
 DBV TECHNOLOGIES S ADBVT |
| 0.65% | — | $15.0M | 915,000 | $0 | 0 | +915,000 | New Buy |
| PPARABILIS MEDICINES INCPBLS |
| 0.62% | — | $14.4M | 525,000 | $0 | 0 | +525,000 | New Buy |
 RHYTHM PHARMACEUTICALS INCRYTM |
| 0.6% | 1.95% | $13.9M | 125,000 | $39.1M | 450,000 | -325,000-72.22% | Reduce |
| VVOR BIOPHARMA INCVOR |
| 0.52% | 0.67% | $12.0M | 650,000 | $13.4M | 750,000 | -100,000-13.33% | Reduce |
 SCHOLAR ROCK HLDG CORPSRRK |
| 0.47% | — | $11.0M | 200,000 | $0 | 0 | +200,000 | New Buy |
| IIMMIX BIOPHARMA INC COMIMMX |
| 0.44% | 0.56% | $10.3M | 1.0M | $11.2M | 1.2M | -225,000-18.37% | Reduce |
| QQ32 BIO INC COMQTTB |
| 0.44% | — | $10.2M | 800,000 | $0 | 0 | +800,000 | New Buy |
| OODYSSEY THERAPEUTICS INCODTX |
| 0.42% | — | $9.8M | 521,736 | $0 | 0 | +521,736 | New Buy |
 ANNEXON INCANNX |
| 0.37% | — | $8.6M | 1.5M | $0 | 0 | +1.5M | New Buy |
