PTC THERAPEUTICS INC PTCT
10.95% 9.6% $75.0M 918,846 $62.8M 921,607 -2,761 -0.30% Reduce ACADIA HEALTHCARE COMPANY IN ACHC
10.59% — $72.5M 2.9M $0 0 +2.9M New Buy INSMED INC INSM
6.45% 10.39% $44.1M 413,980 $67.9M 415,269 -1,289 -0.31% Reduce A ANAPTYSBIO INC ANAB
5.95% 5.41% $40.7M 603,489 $35.4M 638,161 -34,672 -5.43% Reduce BIOMARIN PHARMACEUTICAL INC BMRN
5.71% 5.92% $39.1M 682,777 $38.7M 685,182 -2,405 -0.35% Reduce D DYNE THERAPEUTICS INC DYN
5.35% 4.58% $36.6M 1.6M $30.0M 1.7M -5,451 -0.33% Reduce UNITED THERAPEUTICS CORP DEL UTHR
4.96% 5.7% $33.9M 62,587 $37.2M 62,809 -222 -0.35% Reduce DISC MEDICINE INC IRON
4.45% 3.93% $30.5M 416,646 $25.7M 401,719 +14,927 +3.72% Add BIOGEN INC BIIB
4.43% 3.95% $30.3M 140,279 $25.8M 140,719 -440 -0.31% Reduce I IOVANCE BIOTHERAPEUTICS INC IOVA
3.22% 3.41% $22.0M 5.3M $22.3M 6.3M -1.1M -16.59% Reduce U ULTRAGENYX PHARMACEUTICAL IN RARE
2.91% 1.91% $19.9M 596,495 $12.5M 596,495 0 0.00% Unchanged N NOVOCURE LTD NVCR
2.83% 2.13% $19.4M 1.3M $14.0M 1.3M 0 0.00% Unchanged SYNDAX PHARMACEUTICALS INC SNDX
2.76% 3.09% $18.9M 864,986 $20.2M 864,986 0 0.00% Unchanged ANNEXON INC ANNX
2.46% 2.5% $16.8M 2.9M $16.3M 2.9M 0 0.00% Unchanged B BICARA THERAPEUTICS INC BCAX
2.39% 1.67% $16.3M 550,408 $10.9M 550,408 0 0.00% Unchanged C CAREDX INC CDNA
2.22% 1.41% $15.2M 531,870 $9.2M 531,870 0 0.00% Unchanged C CELLDEX THERAPEUTICS INC NEW CLDX
2.17% 1.44% $14.9M 399,856 $9.4M 296,408 +103,448 +34.90% Add C COMPASS THERAPEUTICS INC CMPX
1.87% 1.23% $12.8M 5.8M $8.0M 1.5M +4.3M +285.06% Add ALKERMES PLC ALKS
1.86% 1.31% $12.7M 242,560 $8.6M 242,560 0 0.00% Unchanged F FIRST TRACKS BIOTHERAPEUTICS TRAX
1.77% — $12.1M 603,489 $0 0 +603,489 New Buy PROTHENA CORP PLC PRTA
1.64% 1.8% $11.2M 1.1M $11.7M 1.2M -65,413 -5.41% Reduce T TRAVERE THERAPEUTICS INC TVTX
1.39% 1.05% $9.5M 167,525 $6.8M 230,453 -62,928 -27.31% Reduce TAYSHA GENE THERAPIES INC TSHA
1.38% 0.95% $9.5M 1.4M $6.2M 1.4M 0 0.00% Unchanged A ACLARIS THERAPEUTICS INC COM ACRS
1.25% 0.93% $8.5M 1.6M $6.1M 1.6M 0 0.00% Unchanged AGIOS PHARMACEUTICALS INC AGIO
1.16% 1.11% $7.9M 213,601 $7.2M 213,601 0 0.00% Unchanged C CAPRICOR THERAPEUTICS INC COM NEW CAPR
0.81% 1.07% $5.5M 229,763 $7.0M 229,763 0 0.00% Unchanged ALIGN TECHNOLOGY INC COM USD0.0001 ALGN
0.77% 1.09% $5.3M 31,389 $7.1M 41,520 -10,131 -24.40% Reduce O ORUKA THERAPEUTICS INC COM ORKA
0.47% 0.45% $3.2M 33,546 $2.9M 59,985 -26,439 -44.08% Reduce XENON PHARMACEUTICALS INC XENE
0.45% 0.46% $3.1M 51,345 $3.0M 51,345 0 0.00% Unchanged NEUROCRINE BIOSCIENCES INC NBIX
0.45% 0.37% $3.1M 18,117 $2.4M 18,117 0 0.00% Unchanged EDWARDS LIFESCIENCES CORP EW
0.44% 0.41% $3.0M 33,640 $2.7M 33,640 0 0.00% Unchanged STOKE THERAPEUTICS INC STOK
0.4% 0.42% $2.8M 84,631 $2.8M 84,631 0 0.00% Unchanged CYTOKINETICS INC CYTK
0.4% 0.32% $2.7M 32,195 $2.1M 32,195 0 0.00% Unchanged P PYXIS ONCOLOGY INC COMMON STOCK PYXS
0.38% 0.23% $2.6M 864,277 $1.5M 1.0M -146,233 -14.47% Reduce E EHEALTH INC COM EHTH
0.32% 0.29% $2.2M 1.5M $1.9M 1.5M 0 0.00% Unchanged CRISPR THERAPEUTICS CRSP
0.32% 0.29% $2.2M 39,605 $1.9M 39,605 0 0.00% Unchanged S SAGIMET BIOSCIENCES INC SGMT
0.28% — $1.9M 250,000 $0 0 +250,000 New Buy N NUVATION BIO INC NUVB
0.27% 0.33% $1.9M 326,609 $2.2M 508,846 -182,237 -35.81% Reduce BIONTECH SE FUNSPONSORED ADR 1 ADR REPS 1 ORD SHS BNTX
0.27% 0.27% $1.8M 19,614 $1.7M 19,614 0 0.00% Unchanged COMPASS PATHWAYS ADR A FUNSPONSORED ADR 1 ADR REPS 1 ORD SHS CMPS
0.24% 0.1% $1.6M 115,616 $639,356 115,616 0 0.00% Unchanged HUMANA INC COM HUM
0.23% 0.11% $1.6M 3,985 $690,959 3,985 0 0.00% Unchanged N NEWAMSTERDAM PHARMA COMPANY NAMS
0.22% — $1.5M 44,359 $0 0 +44,359 New Buy M MIRUM PHARMACEUTICALS MIRM
0.2% — $1.4M 348,808 $0 0 +348,808 New Buy V VERASTEM INC COM NEW VSTM
0.17% 0.2% $1.2M 309,685 $1.3M 246,093 +63,592 +25.84% Add MADRIGAL PHARMACEUTICALS INC MDGL
0.14% 0.14% $959,530 1,787 $935,441 1,787 0 0.00% Unchanged U UROGEN PHARMA LTD URGN
0.13% 0.07% $901,600 24,500 $440,510 24,500 0 0.00% Unchanged BICYCLE THERAPEUTICS PLC SPON ADS EACH REP 1 ORD SHS BCYC
0.13% 0.14% $856,014 201,890 $936,770 201,890 0 0.00% Unchanged XERIS BIOPHARMA HLDGS IN XERS
0.12% 0.09% $826,927 104,410 $605,578 104,410 0 0.00% Unchanged A ABEONA THERAPEUTICS INC COM NEW ABEO
0.1% 0.07% $672,786 108,865 $487,715 108,865 0 0.00% Unchanged I INSPIRE MED SYS INC INSP
0.06% 0.07% $391,319 8,772 $452,460 8,772 0 0.00% Unchanged 
